MEMORIA CIENTIFICA 2019

Servicio de Dermatología.

Hospital Universitario San Cecilio

 

PUBLICACIONES

 

Dermatología General

 

1. Navarro-Triviño FJ, Sanchez-Parera R, Ruiz-Villaverde R. Secukinumab-induced paradoxical hidradenitis suppurativa. Dermatol Ther. 2020 Jan;33(1):e13150.

2. Navarro-Triviño FJ. Asymptomatic eruptive facial papules. Rev Clin Esp. 2019 Oct 22. pii: S0014-2565(19)30222-X. doi: 10.1016/j.rce.2019.07.013.

3. Pereyra-Rodriguez JJ, Dominguez-Cruz JJ, Hernandez-Montoya C, Galan-Gutiérrez M, Martín Carrasco P, Alcántara Luna S, Navarro-Triviño FJ, Del Pozo J,Ruiz-Villaverde R. Entwicklung und Validierung eines Fragebogens zur Messung des Empowerments bei erwachsenen Patienten mit atopischer Dermatitis. Der DATEMP-Fragebogen. J Dtsch Dermatol Ges. 2019 Sep;17(9):923-932.

4. Navarro-Triviño FJ, Ortego Centeno N. Linear lupus panniculitis of the scalp with good response to thalidomide. Lupus. 2019 Oct;28(11):1380-1382.

5. Navarro-Triviño FJ. Tattoo skin reaction treatment with topical allopurinol: a good alternative. Int J Dermatol. 2019 Dec;58(12):e250-e252.

6. Navarro-Triviño FJ, Linares-González L, Ródenas-Herranz T. Terry's nails as the first clinical sign of autoimmune hepatitis. Rev Clin Esp. 2019 Jun 29. pii: S0014-2565(19)30156-0.

7. Navarro-Triviño FJ. Neutrophilic dermatosis and myelodysplastic syndrome. Med Clin (Barc). 2020 Jan 24;154(2):73.

8. Linares González L, Aguayo Carreras P, Rueda Villafranca B, Navarro-Triviño FJ. Chondroid Syringoma Mimicking Basal Cell Carcinoma. Actas Dermosifiliogr.2019 May 25. pii: S0001-7310(19)30126-7.

9. Navarro-Triviño FJ, Ruíz-Villaverde R. Yellow keratotic palmoplantar papules and chronic abdominal pain. Rev Clin Esp. 2019 Apr 20. pii:S0014-2565(19)30103-1.

10. Schneller-Pavelescu L, Vergara-de Caso E, Martorell A, Romaní J, Lázaro M, Vilarrasa E, Díaz-Ley B, Vázquez-Osorio I, Segura Palacios JM, Azaña JM, González-López MA, Cañueto J, Molina-Leyva A, Leiva-Salinas M, Navarro-Triviño FJ, Sánchez-Payá J, Pascual JC. Reply to "Comment on 'Interruption of oral clindamycin plus rifampicin therapy in patients with hidradenitis suppurativa: an observational study to assess prevalence and causes' ". J Am Acad Dermatol. 2019 Mar 11. pii: S0190-9622(19)30366-4.

11. Navarro-Triviño FJ, Arias-Santiago S, Gilaberte-Calzada Y. Vitamin D and the Skin: A Review for Dermatologists. Actas Dermosifiliogr. 2019 May;110(4):262-272.

12. Schneller-Pavelescu L, Vergara-de Caso E, Martorell A, Romaní J, Lázaro M, Vilarrasa E, Díaz-Ley B, Vázquez-Osorio I, Segura Palacios JM, Azaña JM, González-López MA, Cañueto J, Molina-Leyva A, Leiva-Salinas M, Navarro-Triviño FJ, Sánchez-Payá J, Pascual JC. Interruption of oral clindamycin plus rifampicin therapy in patients with hidradenitis suppurativa: An observational study to assess prevalence and causes. J Am Acad Dermatol. 2019 May;80(5):1455-1457.

13. Ramos-García P, González-Moles MÁ, González-Ruiz L, Ayén Á, Ruiz-Ávila I, Navarro-Triviño FJ, Gil-Montoya JA. An update of knowledge on cortactin as a metastatic driver and potential therapeutic target in oral squamous cell carcinoma. Oral Dis. 2019 May;25(4):949-971.

14. Pérez-López I, Aguayo-Carreras P. [Lichen striatus]. An Pediatr (Barc). 2019 Dec;91(6):418.

15. Molina-Leyva A, Cuenca-Barrales C. Pruritus and Malodour in Patients with Hidradenitis Suppurativa: Impact on Quality of Life and Clinical Features Associated with Symptom Severity. Dermatology. 2020;236(1):59-65.

16. Cuenca-Barrales C, Molina-Leyva A. Risk Factors of Sexual Dysfunction in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study. Dermatology. 2020;236(1):37-45.

17. Molina-Leyva A, Salvador-Rodriguez L, Martinez-Lopez A, Cuenca-Barrales C. Effectiveness, safety and tolerability of drainage and punch-trocar-assisted cryoinsufflation (cryopunch) in the treatment of inflammatory acute fluid collections in hidradenitis suppurativa patients. J Eur Acad Dermatol Venereol.2019 May;33(5):e221-e223.

18. Molina-Leyva A, Cuenca-Barrales C. Adolescent-Onset Hidradenitis Suppurativa: Prevalence, Risk Factors and Disease Features. Dermatology. 2019;235(1):45-50.

19. Cancela-Díez B, López-Delgado D, Aneiros-Fernandez J, Ruiz-Villaverde R. A Case of Intertriginous and Flexural Exanthema caused by Amoxicillin. Sultan Qaboos Univ Med J. 2019 Nov;19(4):e369-e371. doi: 10.18295/squmj.2019.19.04.014.

20. Navarro-Triviño FJ, Linares-Gonzalez L, Ródenas-Herranz T, Ruiz-Villaverde R. Successful treatment of micaceous balanitis with 5% topical imiquimod: case report and review of the literature. Int J Dermatol. 2019 Dec 17

21. Ródenas-Herranz T, Vega-Castillo JJ, Ruiz-Villaverde R. sQUIZ your knowledge! Facial solid oedema of unknown origin. Eur J Dermatol. 2019 Oct 1;29(5):576-577.

22. Linares-Gonzalez L, Ródenas-Herranz T, Ruiz-Villaverde R. sQUIZ your knowledge! A painful nodule on the forehead of an elderly patient. Eur J Dermatol. 2019 Oct 1;29(5):574-575.

26. Navarro-Triviño FJ, Mérida-Fernández C, Linares-Gonzalez L, Ruiz-Villaverde R. Is omalizumab safe and effective in oncological patients? Dermatol Ther. 2019 Nov;32(6):e13115.

27. Linares-Gonzalez L, Ramos-Pleguezuelos F, Ruiz-Villaverde R. sQUIZ your knowledge! Polycyclic annular plaques on the back of an elderly patient. Eur J Dermatol. 2019 Aug 1;29(4):451-453.

28. Navarro-Triviño FJ, Lopez Gomez J, R Pleguezuelos FM, Ruiz-Villaverde R. Pemphigoid lichen planus consequential to vildagliptin: a rare variant of bullous pemphigoid? Int J Dermatol. 2019 Sep 12.

29. Pereyra-Rodriguez JJ, Dominguez-Cruz JJ, Hernandez-Montoya C, Galan-Gutiérrez M, Carrasco PM, Luna SA, Navarro-Triviño FJ, Del Pozo J, Ruiz-Villaverde R. Development and validation of a questionnaire to measure empowerment in adult patients with atopic dermatitis. The DATEMP questionnaire. J Dtsch Dermatol Ges. 2019 Sep;17(9):923-931.

30. Cuenca-Barrales C, Espadafor-López B, Martínez-López A, Cancela-Díez B, Ruiz-Villaverde R. Bullous pemphigoid in a patient treated with nivolumab. Dermatol Ther. 2019 Sep;32(5):e13030. doi: 10.1111/dth.13030. Epub 2019 Aug 1.

31.Cuenca-Barrales C, Aguayo-Carreras P, Bueno-Rodriguez A, Ruiz-Villaverde R. Ultrasound in the Evaluation of Cutaneous Metastases of Internal Tumors. Actas Dermosifiliogr. 2019 Jul - Aug;110(6):506-509.

32. Cuenca-Barrales C, Espadafor-Lopez B, Ruiz-Villaverde R. Majocchís granuloma on the genital area. J Obstet Gynaecol. 2020 Apr;40(3):438-439.

33. Espadafor-López B, Cuenca-Barrales C, Salvador-Rodriguez L, Ruiz-Villaverde R. Iatrogenic Kaposi's Sarcoma Successfully Treated with Topical Timolol. Actas Dermosifiliogr. 2019 Jun 14. pii: S0001-7310(19)30214-5.

34. Dominguez-Cruz J, Ruiz-Villaverde R. The '5R + R' Rule: A simple and comprehensive method for diagnosis of actinic keratosis. Sultan Qaboos Univ Med J. 2019 Feb;19(1):e81-e82.

35. Ruiz-Villaverde R, Rueda-Villafranca B, Galvez-Moreno MR. Palmoplantar Lichen Planus: A diagnosis to keep in mind. Sultan Qaboos Univ Med J. 2019 Feb;19(1):e79-e80.

36. Hernandez-Montoya C, Ruiz-Villaverde R. The Role of Tofacitinib in the Management of Alopecia Totalis. Sultan Qaboos Univ Med J. 2019 Feb;19(1):e77-e78.

37. Martorell A, Alfageme Roldán F, Vilarrasa Rull E, Ruiz-Villaverde R, Romaní De Gabriel J, García Martínez F, Vidal Sarro D, Velasco Pastor M, Ciudad Blanco C, Segura Palacios JM, Rodríguez Bandera AI, Pascual Ramírez JC, Sancho Sánchez C, Michelena De Gorosábel N, Wortsman X. Ultrasound as a diagnostic and management tool in hidradenitis suppurativa patients: a multicentre study. J Eur  Acad Dermatol Venereol. 2019 Nov;33(11):2137-2142.

38. Armario-Hita JC, Pereyra-Rodriguez J, Silvestre JF, Ruiz-Villaverde R, Valero A, Izu-Belloso R, Jáuregui-Presa I, Curto-Barredo L, Figueras-Nart I, Herranz-Pinto P, Herraez-Herrera L, Ortiz-de-Frutos FJ, Martinez-Pilar L, Sastre  J, Serra-Baldrich E. Treatment of moderate-to-severe atopic dermatitis with dupilumab in real clinical practice: a multicentre, retrospective case series. Br J Dermatol. 2019 Nov;181(5):1072-1074.

39. Cuenca-Barrales C, Ruiz-Villaverde R, Molina-Leyva A. Sexual Distress in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study. J Clin Med. 2019 Apr 18;8(4).

40.Navarro-Triviño FJ, González-Ruiz L, Ruíz-Villaverde R. Flower and Milium: A Tatoo With Points in Relief. Actas Dermosifiliogr. 2019 Apr 15. pii:S0001-7310(19)30117-6.

41.Ruiz-Villaverde R, Dominguez-Cruz J, Armario-Hita JC, Martinez-Pilar L, Alcantara-Luna S, Pereyra-Rodriguez JJ. Fifty-two week follow-up safety and effectiveness results of dupilumab treatment of moderate-to-severe atopic dermatitis from a retrospective, multicentric series. Dermatol Ther. 2019 Jul;32(4):e12931.

42. Aguayo-Carreras P, Cuenca-Barrales C, Perez-López I, Ruiz-Villaverde R, Tercedor-Sanchez J. Successful response to liposomal amphotericin B in mucosal leishmaniasis in glans resistant to intralesional pentavalent. Int J Dermatol.2019 Jul;58(7):e137-e138.

43.Ruiz-Villaverde R, Cuenca-Barrales C, Linares-Gonzalez L, Ródenas-Herranz T. Alopecia universalis. Partial response to tofacitinib. Med Clin (Barc). 2019 Aug 2;153(3):e15.

44. Fernández-Crehuet P, Ruiz-Villaverde R. Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus: More Than a Coincidence. Actas Dermosifiliogr. 2019;110(5):417-419.

45.López-Delgado D, Cuenca-Barrales C, Ruiz-Villaverde R. [Beyond mycosis and warts on feet…]. Aten Primaria. 2019 Feb;51(2):122.

46.Ruiz-Villaverde R, Dominguez-Cruz J, Armario-Hita JC, Martinez-Pilar L, Alcantara-Luna S, Pereyra-Rodriguez JJ. Dupilumab: short-term effectiveness and security in real clinical practice - A retrospective multicentric study. J Eur Acad Dermatol Venereol. 2019 Jan;33(1):e21-e22. doi: 10.1111/jdv.15118. Epub 2018

47. Aguayo Carreras P, Tercedor Sánchez J, Ruiz Villaverde R. FR- Risk of Nonmelanoma Skin Cancer in Patients on Hemodialysis. Actas Dermosifiliogr. 2019 May;110(4):313-314.

 

Unidad de Melanoma y Oncologia Cutánea

 

1.Husein-ElAhmed H, Almazan-Fernandez FM, Husein-ElAhmed S. Ingenol mebutate versus imiquimod versus diclofenac for actinic cheilitis: a 6-month follow-up clinical study. Clin Exp Dermatol. 2019 Mar;44(2):231-234.

Unidad de Fototerapia

 

1.Cuenca-Barrales C, Navarro-Triviño FJ, Vega-Castillo JJ, Rodríguez-Pérez J, Ruiz-Villaverde R, Espelt-Otero JL. Cutaneous hardening in a patient with systemic sclerosis successfully treated with UVA-1 phototherapy. Dermatol Ther.2019 Nov;32(6):e13133

 

Unidad de Inmunoalergia

 

1. Navarro-Triviño FJ, Cuenca-Manteca J, Ruiz-Villaverde R. Allergic contact dermatitis with systemic symptoms caused by VenaSeal. Contact Dermatitis. 2020 Mar;82(3):185-187.

2. Navarro-Triviño FJ, Ruiz-Villaverde R. Allergic contact dermatitis of the hands caused by thiurams in bicycle cuffs. Contact Dermatitis. 2020 Mar;82(3):176-177.

3. Navarro-Triviño FJ, Ruiz-Villaverde R. Chronic foot eczema caused by Bis-GMA from composite work protection boots. Contact Dermatitis. 2020 Mar;82(3):167-168.

4. Ródenas-Herranz T, Navarro-Triviño FJ, Linares-González L, Ruiz-Villaverde R, Brufau-Redondo C, Mercader-García P. Acrylate allergic contact dermatitis caused by hair prosthesis fixative. Contact Dermatitis. 2020 Jan;82(1):62-64.

5. Navarro Triviño FJ, Cuenca-Barrales C, Ruiz-Villaverde R. Eugenol allergy mimicking recurrent aphthous stomatitis and burning mouth syndrome. Contact Dermatitis. 2019 Dec;81(6):462-463.

6. Navarro-Triviño FJ, Cuenca-Barrales C, Vega-Castillo JJ, Ruiz-Villaverde R. Chronic hand eczema and hepatogenic pruritus with good response to apremilast. Dermatol Ther. 2019 May;32(3):e12879.

 

Unidad de Tricología

 

1. Porriño-Bustamante ML, Fernández-Pugnaire MA, Arias-Santiago S. A.Cross-sectional Study of Rosacea and Risk Factors in Women with Frontal Fibrosing Alopecia. Acta Derm Venereol. 2019 Nov 1;99(12):1099-1104.

2. Moreno-Arrones OM, Saceda-Corralo D, Rodrigues-Barata AR, Castellanos-González M, Fernández-Pugnaire MA, Grimalt R, Hermosa-Gelbard A, Bernárdez C, Molina-Ruiz  AM, Ormaechea-Pérez N, Fernández-Crehuet P, Arias-Santiago S, Alonso MJ, Jaén-Olasolo P, Vaño-Galván S. Factors influencing frontal fibrosing alopecia severity: a multicentre cross-sectional study. J Eur Acad Dermatol Venereol. 2019 Sep;33(9):e315-e316.

3. Porriño-Bustamante ML, López-Nevot MÁ, Aneiros-Fernández J, Casado-Ruiz J, García-Linares S, Pedrinacci-Rodríguez S, García-Lora E, Martín-Casares MA, Fernández-Pugnaire MA, Arias-Santiago S. Study of Human Leukocyte Antigen (HLA) in 13 cases of familial frontal fibrosing alopecia: CYP21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA-A*33:01; B*14:02; C*08:02 as a genetic marker. Australas J Dermatol. 2019 Aug;60(3):e195-e200.

4. Porriño-Bustamante ML, López-Nevot MÁ, Aneiros-Fernández J, García-Lora E, Fernández-Pugnaire MA, Arias-Santiago S. Familial frontal fibrosing alopecia: A cross-sectional study of 20 cases from nine families. Australas J Dermatol. 2019 May;60(2):e113-e118.

5. Moreno-Arrones OM, Saceda-Corralo D, Rodrigues-Barata AR, Castellanos-González M, Fernández-Pugnaire MA, Grimalt R, Hermosa-Gelbard A, Bernárdez C, Molina-Ruiz  AM, Ormaechea-Pérez N, Fernández-Crehuet P, Vaño-Galván S. Risk factors associated with frontal fibrosing alopecia: a multicentre case-control study. Clin Exp Dermatol. 2019 Jun;44(4):404-410.

 

Unidad de Psoriasis

 

1. Aguayo-Carreras P, Ruiz-Carrascosa JC, Molina-Leyva A. Type D personality is associated with poor quality of life, social performance, and psychological impairment in patients with moderate to severe psoriasis: A cross-sectional study of 130 patients. Indian J Dermatol Venereol Leprol. 2019 Dec 17. doi: 10.4103/ijdvl.IJDVL_114_19.

2. Molina-Leyva A, Cuenca-Barrales C, Vega-Castillo JJ, Ruiz-Carrascosa JC, Ruiz-Villaverde R. Adherence to Mediterranean diet in Spanish patients with psoriasis: Cardiovascular benefits? Dermatol Ther. 2019 Mar;32(2):e12810.

3. Molina-Leyva A, Salvador-Rodriguez L, Martinez-Lopez A, Ruiz-Carrascosa JC, Arias-Santiago S. Association Between Psoriasis and Sexual and Erectile Dysfunction in Epidemiologic Studies: A Systematic Review. JAMA Dermatol. 2019 Jan 1;155(1):98-106.

4. Ruiz-Villaverde R, Rodriguez-Fernandez-Freire L, Galán-Gutierrez M, Martinez-Pilar L. Efficacy of secukinumab in psoriasis and psoriatic arthritis: A retrospective multicentre study. Med Clin (Barc). 2019 Feb 1. pii:S0025-7753(19)30006-5.

5.Ribera M, Ros S, Madrid B, Ruiz-Villaverde R, Rebollo F, Gómez S, Loza E, Carretero G. Consensus Statement on the Psychological Needs of Patients With Chronic Inflammatory Skin Diseases. Actas Dermosifiliogr. 2019 Mar;110(2):102-114.

 

ENSAYOS CLINICOS ACTIVOS

 

Título: A Multicenter, Randomized, Open Label, Efficacy Assessor-Blinded Study of Risankizumab Compared to Secukinumab for the Treatment of Adult Subjects with Moderate to Severe Plaque Psoriasis who are Candidates for Systemic Therapy. Phase 3. ClinicalTrials.gov.Identifier: NCT03478787

Carácter: Europeo

Laboratorio responsable: Abbvie SA

Investigador principal: Jose C Ruiz Carrascosa

Investigador colaborador: Ricardo Ruiz Villaverde

 

Título: A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adolescent and Adult Subjects with Moderate to Severe Atopic Dermatitis. ClinicalTrials.gov.Identifier: NCT03569293

Carácter: Europeo

Laboratorio responsable: Abbvie SA

Investigador principal: Jose C Ruiz Carrascosa

Investigador colaborador: Ricardo Ruiz Villaverde

 

ESTUDIOS OBSERVACIONALES NO EPA

 

Título: APPRECIATE™ (Experiencia del tratamiento clínico con apremilast en psoriasis): Estudio observacional, multicéntrico, retrospectivo de la experiencia real de pacientes con psoriasis tratados con apremilast en la práctica clínica dermatológica.

Código: CC-10004-PSOR-013

Carácter: Europeo

Laboratorio responsable: Cellgene

Investigador principal: Ricardo Ruiz Villaverde

 

PROYECTOS DE FINANCIACION COMPETITIVA

 

Título: La ecografía dermatológica y ecodoppler como técnica diagnostica en tumores cutáneos no melanociticos.

Carácter: Nacional

Código Proyecto FIS: PI16/00726

Investigador principal: M.Elena del Prado  Sanz

Co-investigador: Ricardo Ruiz Villaverde

Dedicación: Compartida

Duracion: 2016-2019

 

Título: Búsqueda de marcadores genéticos predictores de respuesta a nuevos fármacos en el tratamiento de la psoriasis

Carácter: Nacional

Código Proyecto: EDT-SIA-2017-02

Investigador principal: Esteban Daudén Tello

Co-investigador: Ricardo Ruiz Villaverde/Jose C Ruiz Carrascosa

Dedicación: Compartida

Duracion: 2018-2021

 

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